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CHKB / CHKL

choline kinase beta

Choline kinase (CK) and ethanolamine kinase (EK) catalyze the phosphorylation of choline/ethanolamine to phosphocholine/phosphoethanolamine. This is the first enzyme in the biosynthesis of phosphatidylcholine/phosphatidylethanolamine in all animal cells. The highly purified CKs from mammalian sources and their recombinant gene products have been shown to have EK activity also, indicating that both activities reside on the same protein. The choline kinase-like protein encoded by CHKL belongs to the choline/ethanolamine kinase family; however, its exact function is not known. Read-through transcripts are expressed from this locus that include exons from the downstream CPT1B locus.

Gene Name: choline kinase beta
Synonyms: CHKB, Choline kinase beta, Choline kinase-like, CK, CHETK, CKEKB, CHKL, Choline/ethanolamine kinase, Ethanolamine kinase beta, Ethanolamine kinase, MDCMC, Choline kinase-like protein, EK, EKB
Target Sequences: NM_005198 NP_005189.2 Q9Y259

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Products
Proteins (10)
Over-Expression Lysate (6)
Recombinant (4)
CHKB / CHKL (10)
No (10)
GST (1)
His, N-Terminal (1)
Myc-DDK (Flag) (8)
Human (6)
Mouse (1)
293T Cells (3)
E. coli (1)
HEK 293 Cells (5)
Wheat Germ Extract (1)
Purified (1)
CHKB / CHKL Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
45.1 kDa
20 µg/$150
CHKB / CHKL Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
13.3 kDa
20 µg/$150
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293T Cells
Myc-DDK (Flag)
45.1 kDa
20 µg/$150
CHKB / CHKL Protein - 12.5% SDS-PAGE of human CHKB stained with Coomassie Blue
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Wheat Germ Extract
GST
71.7 kDa
10 µg/$479; 25 µg/$670
CHKB / CHKL Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
13.3 kDa
100 µg/$494
CHKB / CHKL Protein - Recombinant Choline Kinase Beta (CHKb) by SDS-PAGE
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E. coli
His, N-Terminal
22.6kDa
10 µg/$271; 50 µg/$382; 200 µg/$762; 100 µg/$610; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
CHKB / CHKL Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
45.1 kDa
100 µg/$494
CHKB / CHKL Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
45.1 kDa
100 µg/$494
CHKB / CHKL Protein - Purified recombinant protein CHKB was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
45.1 kDa
20 µg/$1,107
CHKB / CHKL Protein - Purified recombinant protein CHKB was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
13.3 kDa
20 µg/$1,107
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).