CHD5

chromodomain helicase DNA binding protein 5

Chromatin-remodeling protein that binds DNA through histones and regulates gene transcription. May specifically recognize and bind trimethylated 'Lys-27' (H3K27me3) and non-methylated 'Lys-4' of histone H3. Plays a role in the development of the nervous system by activating the expression of genes promoting neuron terminal differentiation. In parallel, it may also positively regulate the trimethylation of histone H3 at 'Lys-27' thereby specifically repressing genes that promote the differentiation into non-neuronal cell lineages. Tumor suppressor, it regulates the expression of genes involved in cell proliferation and differentiation. Downstream activated genes may include CDKN2A that positively regulates the p53/TP53 pathway, which in turn, prevents cell proliferation. In spermatogenesis, it probably regulates histone hyperacetylation and the replacement of histones by transition proteins in chromatin, a crucial step in the condensation of spermatid chromatin and the production of functional spermatozoa.

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Products

Antibodies (20)

ELISA Kits (5)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (20)

Recombinant (1)

Sandwich (5)

Target

CHD5 (28)

Reactivity

Human (22)

Mouse (5)

Rat (5)

Bovine (1)

Chicken (1)

Dog (1)

Horse (1)

Monkey (2)

Pig (1)

Xenopus (1)

Application

IHC (1)

IHC-P (1)

WB (14)

ELISA (5)

ICC (1)

IF (3)

Peptide-ELISA (2)

Host

rabbit (19)

goat (1)

Isotype

IgG (7)

Clonality

polyclonal pc (20)

Format

96-Well Microplate (1)

96-Well Strip Plate (4)

APC (1)

APC Conjugated (1)

Biotin Conjugated (2)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (10)

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Epitope

aa712-896 (8)

Internal (1)

aa1395-1407 (1)

Publications

No (28)

Sample Type

Plasma (4)

Serum (4)

Tissue Homogenates (1)

Tag

His (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

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CHD5 Antibody LS-C501495

Antibody:

CHD5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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CHD5 Antibody (HRP) LS-C501502

Antibody:

CHD5 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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CHD5 Antibody (Biotin) LS-C501496

Antibody:

CHD5 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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CHD5 Antibody (FITC) LS-C501498

Antibody:

CHD5 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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CHD5 Antibody LS-C816109

Antibody:

CHD5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

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CHD5 Antibody LS-C807170

Antibody:

CHD5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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CHD5 Antibody LS-C781000

Antibody:

CHD5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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CHD5 Antibody LS-C340963

Antibody:

CHD5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$431

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CHD5 Antibody LS-C410113

Antibody:

CHD5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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CHD5 Antibody (aa712-896) LS-C374355

Antibody:

CHD5 Rabbit anti-Human Polyclonal (aa712-896) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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CHD5 Antibody (aa712-896, HRP) LS-C711205

Antibody:

CHD5 Rabbit anti-Human Polyclonal (aa712-896) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593

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CHD5 Antibody (aa712-896, Biotin) LS-C686864

Antibody:

CHD5 Rabbit anti-Human Polyclonal (aa712-896) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348

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CHD5 Antibody (aa712-896, FITC) LS-C693641

Antibody:

CHD5 Rabbit anti-Human Polyclonal (aa712-896) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716

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CHD5 Antibody (aa712-896, APC, Cy7) LS-C734228

Antibody:

CHD5 Rabbit anti-Human Polyclonal (aa712-896) (APC, Cy7) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676

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CHD5 Antibody (aa712-896, APC) LS-C740416

Antibody:

CHD5 Rabbit anti-Human Polyclonal (aa712-896) (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

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CHD5 Antibody (aa712-896, Cy3) LS-C702184

Antibody:

CHD5 Rabbit anti-Human Polyclonal (aa712-896) (Cy3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

Select

CHD5 Antibody (aa712-896, PE) LS-C725265

Antibody:

CHD5 Rabbit anti-Human Polyclonal (aa712-896) (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

• Unconjugated
• HRP
• Biotin
• FITC
• APC, Cy7
• APC
• Cy3
• More...
  • PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC, Cy7
  • APC
  • Cy3
  • PE

Select

CHD5 Antibody LS-C412166

Antibody:

CHD5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

CHD5 Antibody (Internal) LS-C353379

Antibody:

CHD5 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

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CHD5 Antibody (aa1395-1407) LS-C61721

Antibody:

CHD5 Goat anti-Human Polyclonal (aa1395-1407) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Mouse, Dog, Rat, Pig, Horse, Human, Monkey

Applications:

Peptide-ELISA

Format:

Unconjugated

Price:

100 µg/$503

Select

Monkey CHD5 (Sandwich ELISA) ELISA Kit - LS-F42324

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

18.75 - 1200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Human CHD5 (Sandwich ELISA) ELISA Kit - LS-F56188

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

18.75 - 1200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human CHD5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93051

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

222.9 kDa

Price:

20 µg/$215

Select

Human CHD5 Protein (Recombinant His) (aa712-896) - LS-G24693

Source:

E. coli

Tag:

His

Molecular Weight:

25.2 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

Select

Human CHD5 (Sandwich ELISA) ELISA Kit - LS-F23358

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

18.75 - 1200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Viewing 1-25 of 28 product results

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