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CHCHD3

coiled-coil-helix-coiled-coil-helix domain containing 3

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription.

Gene Name: coiled-coil-helix-coiled-coil-helix domain containing 3
Synonyms: CHCHD3, PPP1R22, MINOS3
Target Sequences: NM_017812 NP_060282.1 Q9NX63

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).