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CHCHD10

coiled-coil-helix-coiled-coil-helix domain containing 10

CHCHD10 encodes a mitochondrial protein that is enriched at cristae junctions in the intermembrane space. It may play a role in cristae morphology maintenance or oxidative phosphorylation. Mutations in this gene cause frontotemporal dementia and/or amyotrophic lateral sclerosis-2. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7 and 19.

Gene Name:	coiled-coil-helix-coiled-coil-helix domain containing 10
Synonyms:	CHCHD10, C22orf16, Protein N27C7-4, N27C7-4
Target Sequences:	NM_213720 NP_998885.1 Q8WYQ3

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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