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CHAT

choline O-acetyltransferase

CHAT is an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.

Gene Name: choline O-acetyltransferase
Synonyms: CHAT, Choline acetylase, Choline acetyltransferase, Choline O-acetyltransferase, CMS1A2, CHOACTASE, CMS1A
Target Sequences: NM_020549 NP_065574.3 P28329

☰ Filters
Products
Proteins (6)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (3)
Recombinant (2)
CHAT (6)
No (6)
GST, N-terminus (1)
His, N-Terminal (2)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (1)
CHAT Protein - Recombinant  Choline Acetyltransferase By SDS-PAGE
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E. coli
His-T7
28.0 kDa
10 µg/$273; 50 µg/$392; 100 µg/$625; 200 µg/$782; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029
Select
HEK 293 Cells
His, N-Terminal
~70 kDa
100 µg/$298
Select
HEK 293 Cells
His, N-Terminal
~70 kDa
200 µl/$283
CHAT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
82.4 kDa
100 µg/$710
CHAT Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CHAT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
82.4 kDa
20 µg/$215
Viewing 1-6 of 6 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).