Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer.
|Gene Name:||chromatin assembly factor 1, subunit B (p60)|
|Synonyms:||CHAF1B, CAF-1 subunit B, CAF-I 60 kDa subunit, CAF-I p60, CAF1A, CAF-1, CAF-IP60, CAF1, CAF1P60, M-phase phosphoprotein 7, MPHOSPH7|
|Target Sequences:||NM_005441 NP_005432.1 Q13112|
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