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CFL2 / Cofilin 2

cofilin 2 (muscle)

CFL2 / Cofilin 2 is an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.

Gene Name: cofilin 2 (muscle)
Family/Subfamily: Cytoskeleton
Synonyms: CFL2, Cofilin 2, Cofilin-2, NEM7, Cofilin 2 (muscle), Cofilin, muscle isoform
Target Sequences: NM_138638 NP_619579.1 Q9Y281

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Products
Antibodies (42)
Primary (42)
CFL2 / Cofilin 2 (42)
Human (41)
Mouse (22)
Rat (11)
Bat (5)
Bovine (7)
Chicken (12)
Chimpanzee (3)
Dog (2)
Gibbon (3)
Guinea pig (3)
Hamster (2)
Horse (5)
Monkey (5)
Pig (7)
Zebrafish (3)
IHC (14)
IHC-P (11)
WB (40)
ELISA (16)
ICC (5)
IF (8)
IP (1)
Peptide-ELISA (2)
rabbit (40)
mouse (1)
goat (1)
Product Group
IHCPlus (1)
PathPlus Other (1)
IgG (24)
IgG1,k (1)
monoclonal mc (1)
polyclonal pc (41)
6G9 (1)
APC (1)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (3)
Preservative Free (2)
Unconjugated (22)
aa1-156 (8)
aa25-54 (7)
aa1-10, pSer3 (5)
C-Terminus (4)
aa1-166 (1)
aa130-144 (1)
aa136-152 (1)
aa142-152 (1)
aa92-166 (1)
pSer3 (1)
No (42)
CFL2 / Cofilin 2 Antibody - Anti-CFL2 / Cofilin 2 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CFL2 / Cofilin 2 Goat anti-Human Polyclonal (aa142-152) Antibody
Chicken, Bovine, Rat, Hamster, Pig, Horse, Bat, Mouse, Dog, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
CFL2 / Cofilin 2 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC-P, WB
Unconjugated
50 µl/$460
CFL2 / Cofilin 2 Antibody - Immunoperoxidase of monoclonal antibody to CFL2 on formalin-fixed paraffin-embedded human skeletal muscle. [antibody concentration 8 ug/ml]
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CFL2 / Cofilin 2 Mouse anti-Human Monoclonal (6G9) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µg/$423
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal (pSer3) Antibody
Chicken, Mouse, Human
ELISA, WB
Unconjugated
200 µg/$947
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal (aa1-10, pSer3) (PE) Antibody
Chicken, Mouse, Human
ELISA, WB
PE Conjugated
100 µl/$1,154
CFL2 / Cofilin 2 Antibody - IHC of paraffin-embedded gastric CA using Cofilin 2 antibody at 1:100 dilution.
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal (aa92-166) Antibody
Chicken, Bovine, Mouse, Pig, Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
CFL2 / Cofilin 2 Antibody - Immunohistochemistry of paraffin-embedded human heart tissue at dilution 1:100
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
CFL2 / Cofilin 2 Antibody - Anti-CFL2 rabbit polyclonal antibody at 1:500 dilution. Lane A: Raji Whole Cell Lysate. Lane B: Hela Whole Cell Lysate. Lane C: NCI-H1299 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 18 kDa. Observed band size: 18 kDa. (We are unsure as to the identity of these extra bands.)
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Mouse, Human
ICC, IF, IHC-P, IP, WB
Unconjugated, Preservative Free
100 µl/$412
CFL2 / Cofilin 2 Antibody - Cofilin 2 was detected in paraffin-embedded sections of mouse cardiac muscle tissues using rabbit anti- Cofilin 2 Antigen Affinity purified polyclonal antibody
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CFL2 / Cofilin 2 Antibody
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
CFL2 / Cofilin 2 Antibody - Immunofluorescent analysis of Cofilin 2 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, IHC-P
Unconjugated, Preservative Free
100 µl/$412
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal (aa25-54) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal (aa25-54) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal (aa25-54) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal (aa25-54) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal (aa25-54) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal (aa25-54) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
CFL2 / Cofilin 2 Antibody - Immunohistochemistry of paraffin-embedded human heart tissue at dilution 1:100
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CFL2 / Cofilin 2 Antibody - Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa using Cofilin 2 (muscle) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with alpha-tubulin antibody (Red) at 1:2500.
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal (aa1-166) Antibody
Mouse, Bovine, Pig, Human
ICC, WB
Unconjugated
100 µl/$450
CFL2 / Cofilin 2 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CFL2 / Cofilin 2 Antibody - CFL2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human rectum tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal (aa25-54) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CFL2 / Cofilin 2 Antibody - Fluorescent image of HeLa cells stained with CFL2 Antibody. Antibody was diluted at 1:25 dilution. An Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Alexa Fluor 555 conjugated with Phalloidin (red).
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal (aa130-144) Antibody
Mouse, Human
IF, WB
Unconjugated
400 µl/$393
CFL2 / Cofilin 2 Antibody - Western blot analysis of extracts from Jurkat cells and HeLa cells, using Cofilin antibody.
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CFL2 / Cofilin 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
Viewing 1-25 of 42 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).