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CFL1 / Cofilin

cofilin 1 (non-muscle)

Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation.

Gene Name: cofilin 1 (non-muscle)
Synonyms: CFL1, 18 kDa phosphoprotein, Cofilin, CFL, Cofilin 1 (non-muscle), Cofilin, non-muscle isoform, p18
Target Sequences: NM_005507 NP_005498.1 P23528

Publications (1)

1
Identification and validation of differentially expressed proteins in serum of CSU patients with different duration of wheals using an iTRAQ labeling, 2D-LC-MS/MS. Cao Y, Xu S, Kong W, Cai H, Xu Y. Experimental and therapeutic medicine. 2018 December;16:4527-4536. [Full Text Article] [PubMed:30542401] [PMC:PMC6257644]

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Products
Antibodies (73)
Primary (73)
CFL1 / Cofilin (73)
Human (71)
Mouse (51)
Rat (32)
Bat (1)
Bovine (4)
Dog (1)
Guinea pig (1)
Hamster (1)
Horse (2)
Monkey (10)
Pig (5)
Rabbit (2)
Sheep (5)
Zebrafish (1)
IHC (27)
IHC-P (12)
WB (59)
Flo (8)
DB (7)
ELISA (34)
ICC (3)
IF (9)
IP (5)
Peptide-ELISA (4)
rabbit (69)
mouse (3)
sheep (1)
Product Group
IHCPlus (2)
PathPlus Neuro (1)
IgG (47)
IgG1 (1)
IgG1,k (1)
IgG2a,k (1)
monoclonal mc (4)
polyclonal pc (69)
1A1 (1)
AT1C1 (1)
APC (1)
APC Conjugated (5)
Azide-free (4)
Biotin Conjugated (6)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (5)
Unconjugated (43)
pSer3 (21)
aa3-161 (8)
aa4-32 (7)
aa70-98 (7)
Internal (2)
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aa2-166 (2)
pTyr139 (2)
pTyr140/Ser156 (2)
Asp59 (1)
Met1 (1)
aa1-166 (1)
aa1-50 (1)
aa100-150 (1)
aa122-152 (1)
aa39-88 (1)
p3 (1)
No (73)
CFL1 / Cofilin Antibody - Anti-CFL1 / Cofilin antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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CFL1 / Cofilin Mouse anti-Human Monoclonal (aa1-166) (AT1C1) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
CFL1 / Cofilin Antibody - Anti-CFL1 / Cofilin antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
CFL1 / Cofilin Rabbit anti-Human Polyclonal (aa4-32) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
200 µl/$460
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CFL1 / Cofilin Rabbit anti-Human Monoclonal (pSer3) Antibody
Mouse, Rat, Human, Monkey
ELISA, IF, WB
Unconjugated
100 µl/$694
CFL1 / Cofilin Antibody - Immunofluorescent analysis of Cofilin staining in K562 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 ??C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (Internal) Antibody
Zebrafish, Pig, Mouse, Sheep, Rat, Human
ICC, IF, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
CFL1 / Cofilin Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Sheep, Bovine, Rat, Pig, Human, Monkey
ICC, IF, IHC-P, WB
Unconjugated
50 µl/$460
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (Asp59) Antibody
Mouse, Rat, Human, Monkey
ELISA, WB
Unconjugated
100 µl/$688
CFL1 / Cofilin Antibody - 1:200 staining human meningeal carcinomatosis(MC) tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (pSer3) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CFL1 / Cofilin Antibody - P-Peptide - + Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using cofilin (Ab- 1022) antibody.
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (p3) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
CFL1 / Cofilin Antibody - Immunoperoxidase of monoclonal antibody to CFL1 on formalin-fixed paraffin-embedded human breast cancer. [antibody concentration 1.5 ug/ml]
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CFL1 / Cofilin Mouse anti-Human Monoclonal (1A1) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µg/$423
CFL1 / Cofilin Antibody - Immunohistochemical analysis of Cofilin (pS3) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (pSer3) Antibody
Mouse, Sheep, Bovine, Rat, Pig, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$315
CFL1 / Cofilin Antibody - Immunohistochemistry - Anti-Cofilin Picoband Antibody
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (aa2-166) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CFL1 / Cofilin Antibody - IHC-P: Cofilin antibody testing of human breast cancer tissue
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (aa2-166) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$575
CFL1 / Cofilin Antibody - Immunohistochemistry of paraffin-embedded human appendix tissue at dilution of 1:100
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CFL1 / Cofilin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (aa70-98) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (aa70-98) (Biotin) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (aa70-98) (FITC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (aa70-98) (APC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (aa70-98) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (aa70-98) (PE) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
CFL1 / Cofilin Antibody - IHC of Cofilin (M1)pAb in paraffin-embedded human breast carcinoma tissue.
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (Met1) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
CFL1 / Cofilin Antibody - Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue.
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (pSer3) Antibody
IF, IHC, WB
Unconjugated
20 µl/$287; 50 µl/$341; 100 µl/$431; 200 µl/$539
CFL1 / Cofilin Antibody - Cofilin antibody IHC-paraffin. IHC(P): Mouse Intestine Tissue.
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (aa122-152) Antibody
Rabbit, Mouse, Guinea pig, Sheep, Bovine, Rat, Hamster, Pig, Horse, Bat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
40 µg/$485
CFL1 / Cofilin Antibody - Western blot of CFL1 Antibody in HL-60 cell line lysates (35 ug/lane). CFL1 (arrow) was detected using the purified antibody;
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (aa70-98) Antibody
Mouse, Human
Flo, WB
Unconjugated
400 µl/$393
CFL1 / Cofilin Antibody - P-Peptide - + Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using cofilin (phospho-Ser3) antibody.
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CFL1 / Cofilin Rabbit anti-Human Polyclonal (pSer3) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).