CFI / Complement Factor I

complement factor I

CFI / Complement Factor I is a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uraemic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immmune deposits is another condition associated with mutation of this gene.

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Products

ELISA Kits (16)

Type

Custom (1)

Sandwich (15)

Target

CFI / Complement Factor I (16)

Reactivity

Human (8)

Mouse (2)

Rat (1)

Chicken (1)

Guinea pig (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Format

96-Well Microplate (1)

96-Well Strip Plate (15)

Publications

No (16)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (1)

Cell Supernatant (1)

Plasma (12)

Serum (12)

Tissue Homogenates (4)

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Monkey CFI / Complement Factor I (Sandwich ELISA) ELISA Kit - LS-F42710

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

2.34 - 150 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$863

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Mouse CFI / Complement Factor I (Sandwich ELISA) ELISA Kit - LS-F15495

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$783

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Human CFI / Complement Factor I (Sandwich ELISA) ELISA Kit - LS-F21749

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

2.34 - 150 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$610

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Human CFI / Complement Factor I (Sandwich ELISA) ELISA Kit - LS-F5929

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$798

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Porcine CFI / Complement Factor I (Sandwich ELISA) ELISA Kit - LS-F42709

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

2.34 - 150 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Chicken CFI / Complement Factor I (Sandwich ELISA) ELISA Kit - LS-F42707

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Rabbit CFI / Complement Factor I (Sandwich ELISA) ELISA Kit - LS-F42711

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Guinea pig CFI / Complement Factor I (Sandwich ELISA) ELISA Kit - LS-F42712

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Rat CFI / Complement Factor I (Custom ELISA) ELISA Kit - LS-F15494

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Human CFI / Complement Factor I (Sandwich ELISA) ELISA Kit - LS-F26760

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

2.5 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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Human CFI / Complement Factor I (Sandwich ELISA) ELISA Kit - LS-F34571

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

2.344 - 150 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human CFI / Complement Factor I (Sandwich ELISA) ELISA Kit - LS-F39644

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.29 - 18 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$766

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Mouse CFI / Complement Factor I (Sandwich ELISA) ELISA Kit - LS-F52977

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$870

Select

Human CFI / Complement Factor I (Sandwich ELISA) ELISA Kit - LS-F51662

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

6.25 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$870

Select

Human CFI / Complement Factor I (Sandwich ELISA) ELISA Kit - LS-F74702

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

3.13 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Supernatant, Plasma, Serum

Price:

1 Plate/$598

Select

Human CFI / Complement Factor I (Sandwich ELISA) ELISA Kit - LS-F13115

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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