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CETN3
centrin, EF-hand protein, 3
CETN3 contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been identified in human and other mammalian cells, some of which have been shown to be associated with centrosome fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which suggests a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | centrin, EF-hand protein, 3 |
| Synonyms: | CETN3, CEN3, Centrin-3, CDC31 yeast homolog, Centrin, EF-hand protein, 3, EF-hand superfamily member |
| Target Sequences: | NM_004365 NP_004356.2 O15182 |
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