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CEP63

Centrosomal Protein 63kDa

Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication, through centrosomal recruitment of CEP152. Also recruits CDK1 to centrosomes. Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression.

Gene Name:	Centrosomal Protein 63kDa
Synonyms:	CEP63, Centrosomal protein of 63 kDa, Centrosome protein CEP63, Centrosomal protein 63kDa
Target Sequences:	NM_025180 NP_079456.2 Q96MT8

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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