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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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CEP19 / C3orf34
centrosomal protein 19kDa
The protein encoded by this gene localizes to centrosomes and primary cilia and co-localizes with a marker for the mother centriole. This gene resides in a region of human chromosome 3 that is linked to morbid obesity. A homozygous knockout of the orthologous gene in mouse resulted in mice with morbid obesity, hyperphagy, glucose intolerance, and insulin resistance. Mutations in this gene cause morbid obesity and spermatogenic failure (MOSPGF). This gene has a pseudogene on human chromosome 2.
| Gene Name: | centrosomal protein 19kDa |
| Synonyms: | CEP19, C3orf34, Centrosomal protein of 19 kDa, Centrosomal protein 19kDa |
| Target Sequences: | NM_032898 NP_116287.2 Q96LK0 |
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