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CENTB1 / ACAP1

ArfGAP with coiled-coil, ankyrin repeat and PH domains 1

GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.

Gene Name:	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
Synonyms:	ACAP1, Centaurin, beta 1, Centaurin-beta-1, Cnt-b1, KIAA0050, CENTB1
Target Sequences:	NM_014716 NP_055531.1 Q15027

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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