CENPW / C6orf173

centromere protein W

Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation By similarity. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres By similarity. Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPW has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

CENPW / C6orf173 (4)

Publications

No (4)

Tag

GST (1)

GST, N-terminus + His, C-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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CENPW / C6orf173 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121403

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

9.9 kDa

Price:

100 µg/$494

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Human CENPW / C6orf173 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86956

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

9.9 kDa

Price:

20 µg/$150

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Human CENPW / C6orf173 Protein (Recombinant GST, N-terminus + His, C-terminus) - LS-G145247

Source:

E. coli

Tag:

GST, N-terminus + His, C-terminus

Molecular Weight:

37.9 kDa

Price:

50 µg/$419

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Human CENPW / C6orf173 Protein (Recombinant GST) (Full Length) - LS-G37402

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

36.08 kDa

Price:

2 µg/$439

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