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CENPH / CENP-H

centromere protein H

Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.

Gene Name: centromere protein H
Synonyms: CENPH, Centromere protein H, ICEN35, Kinetochore protein CENP-H, NNF1, CENP-H
Target Sequences: NM_022909 NP_075060.1 Q9H3R5

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Products
Proteins (9)
Over-Expression Lysate (2)
Recombinant (7)
CENPH / CENP-H (9)
No (9)
GST (2)
GST, N-terminus (1)
His (1)
His-T7 (2)
Myc-DDK (Flag) (3)
Human (7)
Mouse (1)
293T Cells (1)
E. coli (4)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (4)
CENPH / CENP-H Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
GST, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
CENPH / CENP-H Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
28.3 kDa
20 µg/$150
CENPH / CENP-H Protein - Recombinant Centromere Protein H By SDS-PAGE
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E. coli
His-T7
32.3 kDa
50 µg/$447; 10 µg/$282; 200 µg/$892; 100 µg/$715; 1 mg/$2,005; 500 µg/$1,543; 5 mg/$3,123; 2 mg/$2,192
CENPH / CENP-H Protein - Recombinant Centromere Protein H By SDS-PAGE
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E. coli
His-T7
28.7 kDa
50 µg/$470; 10 µg/$285; 200 µg/$937; 100 µg/$750; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252
CENPH / CENP-H Protein - 12.5% SDS-PAGE of human CENPH stained with Coomassie Blue
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Wheat Germ Extract
GST
52.91 kDa
10 µg/$479; 25 µg/$670
CENPH / CENP-H Protein - 12.5% SDS-PAGE of human CENPH stained with Coomassie Blue
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Wheat Germ Extract
GST
54.9 kDa
10 µg/$479; 25 µg/$670
CENPH / CENP-H Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
28.3 kDa
100 µg/$494
CENPH / CENP-H Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
CENPH / CENP-H Protein - Purified recombinant protein CENPH was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
28.3 kDa
20 µg/$1,107
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).