Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CELSR3 belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation.
|Gene Name:||cadherin, EGF LAG seven-pass G-type receptor 3|
|Family/Subfamily:||GPCR , Orphan-U|
|Synonyms:||CELSR3, Anchor protein, Cadherin family member 11, CDHF11, EGF-like protein 1, EGF-like-domain, multiple 1, Epidermal growth factor-like 1, Flamingo homolog 1, FMI1, KIAA0812, MEGF2, Megf3, HFMI1, Multiple EGF-like domains 2, RESDA1, EGFL1|
|Target Sequences:||NM_001407 NP_001398.2 Q9NYQ7|
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.