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CELA1 / Pancreatic Elastase 1

chymotrypsin-like elastase family, member 1

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B.

Gene Name: chymotrypsin-like elastase family, member 1
Family/Subfamily: Protease , Serine S1
Synonyms: CELA1, El1a, Elastase I, ELA1, Elastase 1, pancreatic, Elastase-1, Pancreatic elastase, Pancreatic elastase I, Porcine pancreatic elastase, Pancreatic elastase 1, Elastase
Target Sequences: NM_001971 NP_001962.3 Q9UNI1

Publications (1)

1
STING signalling protects against chronic pancreatitis by modulating Th17 response. Qinglan Zhao , Murli Manohar , Yi Wei, Stephen J Pandol, Aida Habtezion. Gut. 2019 October;68:1827-1837. [Full Text Article] [PubMed:30705050] [PMC:PMC7069765]

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
CELA1 / Pancreatic Elastase 1 (6)
No (6)
GST (1)
GST, N-terminus (1)
His (1)
His-GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (4)
Mouse (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
CELA1 / Pancreatic Elastase 1 Protein - Recombinant Elastase 1, Pancreatic By SDS-PAGE
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E. coli
His-GST, N-terminus
53.4 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
CELA1 / Pancreatic Elastase 1 Protein - Recombinant Elastase 1, Pancreatic By SDS-PAGE
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E. coli
His
25.0 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
CELA1 / Pancreatic Elastase 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
27.6 kDa
20 µg/$150
CELA1 / Pancreatic Elastase 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
27.6 kDa
100 µg/$494
CELA1 / Pancreatic Elastase 1 Protein - 12.5% SDS-PAGE of human ELA1 stained with Coomassie Blue
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Wheat Germ Extract
GST
54.2 kDa
10 µg/$479; 25 µg/$670
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Wheat Germ Extract
GST, N-terminus
25 µg/$670; 10 µg/$479
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).