Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CEL / Carboxyl Ester Lipase is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein.
|Gene Name:||carboxyl ester lipase|
|Synonyms:||CEL, Bile salt-activated lipase, BAL, BSDL, Bile salt-stimulated lipase, Bile-salt-activated lipase, BSSL, Carboxyl ester hydrolase, Carboxyl ester lipase, CEase, FAPP, Lysophospholipase, pancreatic, Pancreatic lysophospholipase, Sterol esterase, MODY8, Bucelipase, Cholesterol esterase, Fetoacinar pancreatic protein|
|Target Sequences:||NM_001807 NP_001798.2 P19835|
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