CEB1 / HERC5

HECT and RLD domain containing E3 ubiquitin protein ligase 5

Major E3 ligase for ISG15 conjugation. Acts as a positive regulator of innate antiviral response in cells induced by interferon. Functions as part of the ISGylation machinery that recognizes target proteins in a broad and relatively non-specific manner. Catalyzes ISGylation of IRF3 which results in sustained activation, it attenuates IRF3-PIN1 interaction, which antagonizes IRF3 ubiquitination and degradation, and boosts the antiviral response. Catalyzes ISGylation of influenza A viral NS1 which attenuates virulence; ISGylated NS1 fails to form homodimers and thus to interact with its RNA targets. Catalyzes ISGylation of papillomavirus type 16 L1 protein which results in dominant-negative effect on virus infectivity. Physically associated with polyribosomes, broadly modifies newly synthesized proteins in a cotranslational manner. In an interferon-stimulated cell, newly translated viral proteins are primary targets of ISG15.

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Products

Antibodies (15)

Type

Primary (15)

Target

CEB1 / HERC5 (15)

Reactivity

Human (15)

Mouse (1)

Rat (1)

Bovine (6)

Dog (3)

Gibbon (6)

Horse (3)

Monkey (3)

Rabbit (3)

Application

IHC (9)

IHC-P (9)

WB (11)

ELISA (5)

IF (1)

Peptide-ELISA (1)

Host

rabbit (15)

Product Group

IHCPlus (2)

Isotype

IgG (11)

Clonality

polyclonal pc (15)

Format

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

Unconjugated (6)

Epitope

aa287-336 (4)

aa900-949 (4)

Publications

No (15)

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CEB1 / HERC5 Antibody (aa900-949) LS-B9697

Antibody:

CEB1 / HERC5 Rabbit anti-Human Polyclonal (aa900-949) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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CEB1 / HERC5 Antibody (aa900-949, HRP) LS-C444828

Antibody:

CEB1 / HERC5 Rabbit anti-Human Polyclonal (aa900-949) (HRP) Antibody

Reactivity:

Rabbit, Bovine, Horse, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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CEB1 / HERC5 Antibody (aa900-949, Biotin) LS-C444825

Antibody:

CEB1 / HERC5 Rabbit anti-Human Polyclonal (aa900-949) (Biotin) Antibody

Reactivity:

Rabbit, Bovine, Horse, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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CEB1 / HERC5 Antibody (aa900-949, FITC) LS-C444827

Antibody:

CEB1 / HERC5 Rabbit anti-Human Polyclonal (aa900-949) (FITC) Antibody

Reactivity:

Rabbit, Bovine, Horse, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

CEB1 / HERC5 Antibody (aa287-336) LS-B12707

Antibody:

CEB1 / HERC5 Rabbit anti-Human Polyclonal (aa287-336) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

Select

CEB1 / HERC5 Antibody (aa287-336, HRP) LS-C444826

Antibody:

CEB1 / HERC5 Rabbit anti-Human Polyclonal (aa287-336) (HRP) Antibody

Reactivity:

Dog, Bovine, Human, Gibbon

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

CEB1 / HERC5 Antibody (aa287-336, Biotin) LS-C444823

Antibody:

CEB1 / HERC5 Rabbit anti-Human Polyclonal (aa287-336) (Biotin) Antibody

Reactivity:

Dog, Bovine, Human, Gibbon

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

CEB1 / HERC5 Antibody (aa287-336, FITC) LS-C444824

Antibody:

CEB1 / HERC5 Rabbit anti-Human Polyclonal (aa287-336) (FITC) Antibody

Reactivity:

Dog, Bovine, Human, Gibbon

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

CEB1 / HERC5 Antibody LS-C680586

Antibody:

CEB1 / HERC5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

CEB1 / HERC5 Antibody (HRP) LS-C680589

Antibody:

CEB1 / HERC5 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

CEB1 / HERC5 Antibody (Biotin) LS-C680588

Antibody:

CEB1 / HERC5 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

CEB1 / HERC5 Antibody (FITC) LS-C680593

Antibody:

CEB1 / HERC5 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

CEB1 / HERC5 Antibody LS-C666116

Antibody:

CEB1 / HERC5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$351

Select

CEB1 / HERC5 Antibody LS-C803433

Antibody:

CEB1 / HERC5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

CEB1 / HERC5 Antibody LS-C749868

Antibody:

CEB1 / HERC5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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