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CDw218a / IL18R1 is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
|Gene Name:||interleukin 18 receptor 1|
|Synonyms:||IL18R1, CD218a antigen, CDw218a, CD218a, IL-1Rrp, IL1 receptor-related protein, IL18RA, Interleukin-18 receptor 1, IL1RRP, IL-18R-1, Cytokine receptor, IL-18R1, IL1R-rp, Interleukin 18 receptor 1|
|Target Sequences:||NM_003855 NP_003846.1 Q13478|
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