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CDS2

CDP-diacylglycerol Synthase (phosphatidate Cytidylyltransferase) 2

Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13.

Gene Name: CDP-diacylglycerol Synthase (phosphatidate Cytidylyltransferase) 2
Synonyms: CDS2, CDP-DG synthetase 2, CDP-diglyceride synthetase 2, CDP-DG synthase 2, CDP-DAG synthase 2, CDS 2, CDP-diacylglycerol synthase 2, CDP-diglyceride synthase 2
Target Sequences: NM_003818 CAA76270.1 O95674

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
CDS2 (4)
No (4)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
CDS2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CDS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
51.2 kDa
20 µg/$150
CDS2 Protein - 12.5% SDS-PAGE of human CDS2 stained with Coomassie Blue
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Wheat Germ Extract
GST
77.8 kDa
2 µg/$439
CDS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
51.2 kDa
100 µg/$494
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).