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CDRT1
CMT1A duplicated region transcript 1
Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
| Gene Name: | CMT1A duplicated region transcript 1 |
| Synonyms: | CDRT1, FBXW10B, HREP, FBXW10P1, SM25H2, C170RF1, C17ORF1, C17ORF1A |
| Target Sequences: | NM_006382 NP_006373.2 O95170 |
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