CDKN3 / KAP

cyclin-dependent kinase inhibitor 3

CDKN3 encodes a dual specificity protein phosphatase which has been identified as a cyclin-dependent kinase inhibitor and has been shown to interact with, and dephosphorylate human CDK2 kinase. CDKN3 has also been shown to associate with human CDK3 and CDC2. The protein has been reported to remove phosphate from tyrosine residues in model substrates in vitro; however, a mutant protein that bears a lesion in the putative active site cysteine has been shown to lose catalytic activity. In HeLa cells, CDKN3 has been demonstrated to be expressed at the G1 to S transition and overexpression of wild-type CDKN3 has been shown to delay progression through the cell cycle. This gene has been reported to be deleted, mutated, or overexpressed in several kinds of cancers, including breast and prostate cancers.

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Products

ELISA Kits (10)

Type

Cell-Based (1)

Competitive EIA (1)

Sandwich (7)

Sandwich CLIA (1)

Target

CDKN3 / KAP (10)

Reactivity

Human (6)

Mouse (2)

Rat (2)

Monkey (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (2)

96-Well Strip Plate (7)

Publications

No (10)

Sample Type

Adherent Cell Cultures (1)

Plasma (7)

Serum (7)

Tissue Homogenates (4)

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Monkey CDKN3 / KAP (Sandwich ELISA) ELISA Kit - LS-F42990

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Human CDKN3 / KAP (Sandwich ELISA) ELISA Kit - LS-F20885

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human CDKN3 / KAP (CLIA) ELISA Kit - LS-F29297

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Mouse/Human CDKN3 / KAP (Cell-Based ELISA) ELISA Kit - LS-F3219

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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Rat CDKN3 / KAP (Sandwich ELISA) ELISA Kit - LS-F36081

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Mouse CDKN3 / KAP (Competitive EIA) ELISA Kit - LS-F40010

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human CDKN3 / KAP (Sandwich ELISA) ELISA Kit - LS-F32579

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human CDKN3 / KAP (Sandwich ELISA) ELISA Kit - LS-F7407

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$834

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Rat CDKN3 / KAP (Sandwich ELISA) ELISA Kit - LS-F10835

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

Human CDKN3 / KAP (Sandwich ELISA) ELISA Kit - LS-F10836

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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