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CDKN2D / p19 INK4d

cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)

CDKN2D / p19 INK4d is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.

Gene Name: cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
Synonyms: CDKN2D, CDK inhibitor p19INK4d, INK4D, p19, p19 INK4d, p19-INK4D
Target Sequences: NM_079421 NP_001791.1 P55273

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Products
Proteins (11)
Over-Expression Lysate (4)
Recombinant (7)
CDKN2D / p19 INK4d (11)
No (11)
GST (2)
GST, N-terminus (1)
Myc-DDK (Flag) (6)
Human (8)
Mouse (1)
293T Cells (2)
E. coli (4)
HEK 293 Cells (4)
Wheat Germ Extract (1)
Purified (3)
CDKN2D / p19 INK4d Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
17.5 kDa
100 µg/$494
CDKN2D / p19 INK4d Protein - 12.5% SDS-PAGE of human CDKN2D stained with Coomassie Blue
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Wheat Germ Extract
GST
44 kDa
10 µg/$479; 25 µg/$670
CDKN2D / p19 INK4d Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
17.5 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
17.5 kDa
20 µg/$150
CDKN2D / p19 INK4d Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
GST, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
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E. coli
GST
44.9 kDa
50 µg/$483
CDKN2D / p19 INK4d Protein - Purified recombinant protein CDKN2D was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
17.5 kDa
20 µg/$1,107
CDKN2D / p19 INK4d Protein - Purified recombinant protein CDKN2D was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
17.5 kDa
20 µg/$1,107
CDKN2D / p19 INK4d Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
17.5 kDa
100 µg/$494
CDKN2D / p19 INK4d Protein - Recombinant Cyclin Dependent Kinase Inhibitor 2D (CDKN2D) by SDS-PAGE
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E. coli
None
21.4kDa
10 µg/$246; 50 µg/$299; 200 µg/$442; 100 µg/$352; 1 mg/$1,242; 500 µg/$882; 5 mg/$2,097; 2 mg/$1,391
CDKN2D / p19 INK4d Protein - Recombinant Cyclin Dependent Kinase Inhibitor 2D (CDKN2D) by SDS-PAGE
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E. coli
None
21.5kDa
10 µg/$290; 50 µg/$500; 200 µg/$997; 100 µg/$797; 1 mg/$2,139; 500 µg/$1,662; 5 mg/$3,487; 2 mg/$2,329
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).