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CDKL2

cyclin-dependent kinase-like 2 (CDC2-related kinase)

CDKL2 belongs to the CDKL subfamily. CDKL2 has been suggested to be important in learning and memory. Multiple variants of CDKL2 are generated by alternative splicing and intraexonal termination, resulting in diverse carboxy-terminal regulatory domains. Two alternative promoters linked to distinct noncoding exons direct the expression of KKIAMRE.

Gene Name:	cyclin-dependent kinase-like 2 (CDC2-related kinase)
Family/Subfamily:	Protein Kinase , CDKL
Synonyms:	CDKL2, CDC2-related kinase, Cyclin-dependent kinase-like 2, Kkm, KKIAMRE, Protein kinase p56 KKIAMRE, p56 KKIAMRE protein kinase, p56
Target Sequences:	NM_003948 NP_003939.1 Q92772

Publications (1)

Loss of cyclin-dependent kinase-like 2 predicts poor prognosis in gastric cancer, and its overexpression suppresses cells growth and invasion. Fang CL, Uen YH, Chen HK, Hseu YC, Lin CC, Hung ST, Sun DP, Lin KY. Cancer medicine. 2018 0;0: (Human) [Full Text Article] [PubMed:29790675] [PMC:PMC6051174] Related Antibodies: LS-B4479.

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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