CDK3

cyclin-dependent kinase 3

Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

CDK3 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

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CDK3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118697

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.9 kDa

Price:

100 µg/$494

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Human CDK3 Protein (Recombinant His) - LS-G2387

Source:

E. coli

Tag:

His

Price:

50 µg/$361; 250 µg/$739; 10 µg/$261

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Human CDK3 Protein (Recombinant GST) (Full Length) - LS-G27864

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

61.4 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CDK3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75118

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.9 kDa

Price:

20 µg/$150

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Human CDK3 Protein (Recombinant GST, N-terminus) (aa206-305) - LS-G58076

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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