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CDK2AP1 / DOC1

cyclin-dependent kinase 2 associated protein 1

CDK2AP1 is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Name: cyclin-dependent kinase 2 associated protein 1
Synonyms: CDK2AP1, Doc-1, DORC1, Deleted in oral cancer 1, Deleted in oral cancer-1, p12DOC-1, ST19, CDK2-associated protein 1, CDKAP1, DOC1
Target Sequences: NM_004642 NP_004633.1 O14519

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Products
Antibodies (27)
Primary (27)
CDK2AP1 / DOC1 (27)
Human (27)
Mouse (9)
Rat (4)
Bat (3)
Bovine (4)
Chicken (4)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Hamster (3)
Horse (3)
Monkey (3)
Orangutan (3)
Pig (3)
Rabbit (3)
Xenopus (3)
IHC (7)
IHC-P (6)
WB (27)
ELISA (7)
ICC (1)
IF (1)
Peptide-ELISA (3)
rabbit (25)
mouse (2)
Product Group
IHCPlus (3)
IgG (11)
IgG1 (1)
monoclonal mc (2)
polyclonal pc (25)
Clone-R76 (1)
APC (1)
APC Conjugated (1)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (14)
C-Terminus (4)
Internal (2)
30-110 aa, Internal (1)
N-Terminus (1)
aa35-84 (1)
aa51-100 (1)
No (27)
CDK2AP1 / DOC1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CDK2AP1 / DOC1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
CDK2AP1 / DOC1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
CDK2AP1 / DOC1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
CDK2AP1 / DOC1 Antibody - Anti-DOC-1 / CDK2AP1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50-1:100.
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CDK2AP1 / DOC1 Rabbit anti-Human Monoclonal (Internal) (Clone-R76) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
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CDK2AP1 / DOC1 Mouse anti-Human Monoclonal (N-Terminus) Antibody
Human
ICC, WB
Unconjugated
50 µg/$558
CDK2AP1 / DOC1 Antibody - Human, Small Intestine: Formalin-Fixed Paraffin-Embedded (FFPE)
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal (aa51-100) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
CDK2AP1 / DOC1 Antibody - Staining HepG2 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
CDK2AP1 / DOC1 Antibody - Western blot of DOC-1 antibody
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal (30-110 aa, Internal) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CDK2AP1 / DOC1 Antibody - Western blot analysis of extracts from HeLa cells, using CDKA1antibody.
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
CDK2AP1 / DOC1 Antibody - Western blot analysis of the lysates from HeLa cells using CDKAP1 antibody.
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal (aa35-84) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CDK2AP1 / DOC1 Antibody - DOC-1 / CDK2AP1 antibody Western Blot of HeLa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
CDK2AP1 / DOC1 Antibody - DOC-1 / CDK2AP1 antibody Western Blot of HeLa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Hamster, Pig, Horse, Chimpanzee, Gibbon, Orangutan, Human, Monkey
WB
HRP Conjugated
100 µl/$469
CDK2AP1 / DOC1 Antibody - DOC-1 / CDK2AP1 antibody Western Blot of HeLa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Hamster, Pig, Horse, Chimpanzee, Gibbon, Orangutan, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
CDK2AP1 / DOC1 Antibody - DOC-1 / CDK2AP1 antibody Western Blot of HeLa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Hamster, Pig, Horse, Chimpanzee, Gibbon, Orangutan, Human, Monkey
WB
FITC Conjugated
100 µl/$469
CDK2AP1 / DOC1 Antibody - Western Blot; Sample: Recombinant protein.
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
CDK2AP1 / DOC1 Antibody - Western Blot; Sample: Recombinant protein.
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
CDK2AP1 / DOC1 Antibody - Western Blot; Sample: Recombinant protein.
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
CDK2AP1 / DOC1 Antibody - Western Blot; Sample: Recombinant protein.
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
CDK2AP1 / DOC1 Antibody - Western Blot; Sample: Recombinant protein.
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
CDK2AP1 / DOC1 Antibody - Western Blot; Sample: Recombinant protein.
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
CDK2AP1 / DOC1 Antibody - Western blot analysis of CDK2AP1 expression in HUVEC (A); HeLa (B) whole cell lysates.
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal (Internal) Antibody
Chicken, Bovine, Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
CDK2AP1 / DOC1 Antibody - Western blot of HeLa cell lysate using CDKAP1 Antibody
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CDK2AP1 / DOC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
50 µg/$305; 100 µg/$357
Select
CDK2AP1 / DOC1 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-25 of 27 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).