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CDK11A / CDC2L2

cyclin-dependent kinase 11A

CDK11A / CDC2L2 is a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L1, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L1, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions, which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L1 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Many transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of only two have been determined so far.

Gene Name: cyclin-dependent kinase 11A
Family/Subfamily: Protein Kinase , PITSLRE
Synonyms: CDK11A, CDK11, CDC2L3, Cell division cycle 2-like 3, Cyclin-dependent kinase 11A, CDK11-p110, CDK11-p58, PITSLRE A, PITSLRE B, CDC2L2, CDK11-p46, Cell division cycle 2-like 2, p58GTA, PITSLRE, PITSLRE protein kinase beta, PITSLREB
Target Sequences: NP_076916.2 Q9UQ88

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Proteins (3)
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CDK11A / CDC2L2 (3)
No (3)
GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
CDK11A / CDC2L2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
45.7 kDa
20 µg/$150
CDK11A / CDC2L2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
45.7 kDa
100 µg/$494
CDK11A / CDC2L2 Protein
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GST
36.63kDa
10 µg/$479; 25 µg/$670
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).