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CDH17 / Cadherin 17

cadherin 17, LI cadherin (liver-intestine)

CDH17 / Cadherin 17 is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.

Gene Name: cadherin 17, LI cadherin (liver-intestine)
Family/Subfamily: Cadherin , not assigned-Cadherin
Synonyms: CDH17, Cadherin 16, Cadherin-16, HPT1, Human peptide transporter 1, LI cadherin, HPT-1, HPT-1 cadherin, BILL-cadherin, Cadherin, Cadherin-17, LI-cadherin, Liver-intestine cadherin
Target Sequences: NM_004063 NP_004054.3 Q12864

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).