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CDH13 / Cadherin 13

cadherin 13

CDH13 / Cadherin 13 is a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Name: cadherin 13
Family/Subfamily: Cadherin , not assigned-Cadherin
Synonyms: CDH13, Cadherin-13, CDHH, Cdht, Heart cadherin, H-cadherin, T-cad, T-cadherin, Truncated cadherin, p105
Target Sequences: NM_001257 NP_001248.1 P55290

Publications (1)

1
Autocrine IL-8 promotes F-actin polymerization and mediate mesenchymal transition via ELMO1-NF-?B-Snail signaling in glioma. Zhang B, Shi L, Lu S, Sun X, Liu Y, Li H, Wang X, Zhao C, Zhang H, Wang Y. Cancer biology & therapy. 2015 16:898-911. (IHC, WB; Human) [Full Text Article] [PubMed:25870011] [PMC:PMC4623112] Related Antibodies: LS-C119406.

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Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
CDH13 / Cadherin 13 (8)
No (8)
GST (1)
His (1)
His-GST (2)
His-S (1)
Myc-DDK (Flag) (2)
Human (4)
Mouse (1)
Rat (2)
293T Cells (1)
E. coli (4)
HEK 293 Cells (1)
Human Cells (1)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (1)
CDH13 / Cadherin 13 Protein - Recombinant  Cadherin, Heart By SDS-PAGE
Select
E. coli
His
13.6 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
CDH13 / Cadherin 13 Protein - Recombinant  Cadherin, Heart By SDS-PAGE
Select
E. coli
His-S
22.0 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
CDH13 / Cadherin 13 Protein - 12.5% SDS-PAGE of human CDH13 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
104.17 kDa
2 µg/$439
CDH13 / Cadherin 13 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
78.32 kDa
20 µg/$150
Select
Human Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
74.3 kDa
100 µg/$721
CDH13 / Cadherin 13 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
78.32 kDa
100 µg/$494
CDH13 / Cadherin 13 Protein - Recombinant Cadherin, Heart By SDS-PAGE
Select
E. coli
His-GST
50.4 kDa
10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198
CDH13 / Cadherin 13 Protein - Recombinant Cadherin, Heart By SDS-PAGE
Select
E. coli
His-GST
50.4 kDa
10 µg/$287; 50 µg/$480; 100 µg/$767; 200 µg/$957; 1 mg/$2,089; 500 µg/$1,617; 5 mg/$3,347; 2 mg/$2,278
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).