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CDH11 / Cadherin 11
cadherin 11, type 2, OB-cadherin (osteoblast)
CDH11 / Cadherin 11 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
| Gene Name: | cadherin 11, type 2, OB-cadherin (osteoblast) |
| Family/Subfamily: | Cadherin , not assigned-Cadherin |
| Synonyms: | CDH11, CAD11, Cadherin 11, Cadherin-11, CDHOB, OSF-4, Osteoblast cadherin, OB, OB-cadherin, Ventral neural cadherin, Vnc |
| Target Sequences: | NM_001797 NP_001788.2 P55287 |
Publications (4)
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