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CDH1 / E Cadherin

cadherin 1, type 1, E-cadherin (epithelial)

CDH1 / E Cadherin is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.

Gene Name: cadherin 1, type 1, E-cadherin (epithelial)
Family/Subfamily: Cadherin , not assigned-Cadherin
Synonyms: CDH1, CD324, CDHE, Cell-CAM 120/80, E Cadherin, E-Cadherin, ECAD, Epithelial cadherin, Arc-1, UVO, Cadherin-1, CAM 120/80, CD324 antigen, LCAM, Uvomorulin
Target Sequences: NM_004360 NP_004351.1 P12830

Publications (4)

1
Expression, purification, and functional characterization of recombinant PTD-SARA. Huang C, Du R, Zhang P, Meng H, Jia H, Song Y, Li M, Zhang Y, Sun S. Acta biochimica et biophysica Sinica. 2011 43:110-7. (ICC) [PubMed:21266541]
2
Comparison of Different In Vivo Incubation Sites to Produce Tissue-Engineered Small Intestine. Liu Y, Cromeens BP, Wang Y, Fisher K, Johnson J, Chakroff J, Besner GE. Tissue engineering. Part A. 2018 July;4:1138-1147. [Full Text Article] [PubMed:29383981] [PMC:PMC6033308] Related Antibodies: LS-B12414.
3
Benefit of Physiologically Variable Over Pressure-Controlled Ventilation in a Model of Chronic Obstructive Pulmonary Disease: A Randomized Study. Andre Dos Santos Rocha, Roberta Südy, Davide Bizzotto, Miklos Kassai, Tania Carvalho, Raffaele L Dellacà, Ferenc Peták, Walid Habre. Frontiers in physiology. 2021 Jan;11:625777. [Full Text Article] [PubMed:33519528] [PMC:PMC7839245]
4
Physiologically variable ventilation in a rabbit model of asthma exacerbation. André Dos Santos Rocha, Roberta Südy, Ferenc Peták, Walid Habre. British journal of anaesthesia. 2020 December;125:1107-1116. [Full Text Article] [PubMed:33070949]
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CDH1 / E Cadherin ELISA Kit
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Cell-Based
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
CDH1 / E Cadherin ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
CDH1 / E Cadherin ELISA Kit
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Sandwich
96-Well Microplate
Mouse
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$795
CDH1 / E Cadherin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates, Urine
1 Plate/$573
CDH1 / E Cadherin ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Rat
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
CDH1 / E Cadherin ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$627
CDH1 / E Cadherin ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
CDH1 / E Cadherin ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$627
CDH1 / E Cadherin ELISA Kit
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Sandwich
96-Well Strip Plate
Sheep
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$760
CDH1 / E Cadherin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$870
CDH1 / E Cadherin ELISA Kit
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Development Kit
Antibody Pair and Standard
Rat
31.2 - 2000 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,202; 1000 Wells/$1,779
CDH1 / E Cadherin ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$795
CDH1 / E Cadherin ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$870
CDH1 / E Cadherin ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CDH1 / E Cadherin ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CDH1 / E Cadherin ELISA Kit
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Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$929
CDH1 / E Cadherin ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
CDH1 / E Cadherin ELISA Kit
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Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
CDH1 / E Cadherin ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
CDH1 / E Cadherin ELISA Kit
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Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$929
CDH1 / E Cadherin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
CDH1 / E Cadherin ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$717
CDH1 / E Cadherin ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
CDH1 / E Cadherin ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
CDH1 / E Cadherin ELISA Kit
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Sandwich
96-Well Microplate
Chicken
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).