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CDCA1 / NUF2
NUF2, NDC80 kinetochore complex component
CDCA1 / NUF2 is a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described.
| Gene Name: | NUF2, NDC80 kinetochore complex component |
| Synonyms: | NUF2, Cancer/testis antigen 106, CDCA1, HNuf2, Kinetochore protein Nuf2, NUF2R, CT106, HNuf2R, HsNuf2 |
| Target Sequences: | NM_031423 NP_113611.2 Q9BZD4 |
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