CDC45

cell division cycle 45

CDC45 was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

CDC45 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human CDC45 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67790

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

65.4 kDa

Price:

20 µg/$1,107

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Human CDC45 Protein (Recombinant GST, N-terminus) (aa477-566) - LS-G64570

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CDC45 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80726

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

65.4 kDa

Price:

20 µg/$150

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Human CDC45 Protein (Recombinant GST) (Full Length) - LS-G31105

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

88 kDa

Price:

10 µg/$479; 25 µg/$670

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CDC45 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117296

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

65.4 kDa

Price:

100 µg/$494

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