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Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
Gene Name: | CDC42 Small Effector 2 |
Synonyms: | CDC42SE2, CDC42 small effector 2, CDC42 small effector protein 2, SPEC2 |
Target Sequences: | NM_020240 NP_064625.1 Q9NRR3 |
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