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CDC42EP4 / BORG4

CDC42 effector protein (Rho GTPase binding) 4

CDC42EP4 / BORG4 is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.

Gene Name: CDC42 effector protein (Rho GTPase binding) 4
Synonyms: CDC42EP4, CEP4, Binder of Rho GTPases 4, KAIA1777, BORG4, Cdc42 effector protein 4
Target Sequences: NM_012121 NP_036253.2 Q9H3Q1

Publications (1)

1
Regulation of dendrite growth by Cdc42 effector protein-4 in hippocampal neurons in vitro. Lei Hou , Lufeng Wang , Zhijie Zhao , Wei Xu, Yang Wang, Gang Cui. Molecular medicine reports. 2022 April;25:128. [Full Text Article] [PubMed:35169866] [PMC:PMC8867466] Related Antibodies: LS-C804922.

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
CDC42EP4 / BORG4 (5)
No (5)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
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293T Cells
Myc-DDK (Flag)
37.8 kDa
20 µg/$150
CDC42EP4 / BORG4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
37.8 kDa
100 µg/$494
CDC42EP4 / BORG4 Protein - 12.5% SDS-PAGE of human CDC42EP4 stained with Coomassie Blue
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Wheat Germ Extract
GST
64.4 kDa
10 µg/$479; 25 µg/$670
CDC42EP4 / BORG4 Protein - Purified recombinant protein CDC42EP4 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
37.8 kDa
20 µg/$1,107
CDC42EP4 / BORG4 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).