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CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control.
| Gene Name: | CDC42 effector protein (Rho GTPase binding) 2 |
| Synonyms: | CDC42EP2, Binder of Rho GTPases 1, BORG1, Cdc42 effector protein 2, CRIB-containing BOGR1 protein, CEP2 |
| Target Sequences: | NM_006779 NP_006770.1 O14613 |
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