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CDC25B

cell division cycle 25B

CDC25B, a CDC25 dual specificity protein phosphatase, has been shown to affect cell cycle regulation by activating cyclin-dependent kinases Cdk1 and Cdk2 during G2 phase. CDC25B also has been shown to possess oncogenic properties and has been implicated in lung, breast, esophagus, stomach, ovarian, and other cancers. Recently CDC25B has been shown to be a steroid receptor coactivator and this function is independent of the protein phosphatase activity in vitro. CDC25B deficient mice are viable but the female mice are sterile due to the arrest of cell division in oocytes. At least five mRNA splice variants have been documented for CDC25B.

Gene Name: cell division cycle 25B
Family/Subfamily: Protein Phosphatase , CDC25
Synonyms: CDC25B, CDC25B phosphatase, Cell division cycle 25B, M-phase inducer phosphatase 2, CDC25HU2
Target Sequences: NM_021872 NP_068658.1 P30305

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ELISA Kits (3)
Cell-Based Phosphorylation (2)
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CDC25B (3)
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CDC25B ELISA Kit
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Custom
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
1 Plate/$923
CDC25B ELISA Kit
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Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
CDC25B ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).