CDC25A

cell division cycle 25A

CDC25A, a CDC25 dual specificity protein phosphatase, has been shown to activate the cyclin-dependent kinases at different points of the cell cycle. CDC25A has been shown to affect S phase entry and possibly the initiation of mitosis. CDC25A dephosphorylates cyclin dependent kinases, including Cdk2, Cdk4, as well as non cyclin proteins such as the homeodomain transcription factor cut, the proto-oncogene Raf-1. CDC25A has been implicated in many carcinomas, including those of the colon, lymph node, stomach, ovary, breast. CDC25A is located on chromosome 3p21 in an area frequently involved in karyotypic abnormalities in renal carcinomas, small cell carcinomas of the lung, and benign tumors of the salivary gland.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

CDC25A (7)

Publications

No (7)

Tag

6His, N-terminus (1)

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

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Human CDC25A Protein (Recombinant 6His, N-terminus) (Glu2-Leu524) - LS-G26552

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

61 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365; 200 µg/$484

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Human CDC25A Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66211

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.9 kDa

Price:

20 µg/$1,107

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Human CDC25A Protein (Recombinant GST, N-terminus) (aa151-250) - LS-G58060

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CDC25A Protein (Recombinant GST) (Full Length) - LS-G27846

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

83.38 kDa

Price:

2 µg/$439

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Human CDC25A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77174

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.9 kDa

Price:

20 µg/$150

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CDC25A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118399

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.9 kDa

Price:

100 µg/$494

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Human CDC25A Protein (Recombinant His) - LS-G1180

Source:

E. coli

Tag:

His

Price:

10 µg/$361; 50 µg/$739

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