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CDC23
cell division cycle 23
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
| Gene Name: | cell division cycle 23 |
| Synonyms: | CDC23, ANAPC8, APC8, Cell division cycle 23, CUT23, Cyclosome subunit 8 |
| Target Sequences: | NM_004661 NP_004652.2 Q9UJX2 |
Publications (3)
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