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CDA / Cytidine Deaminase

cytidine deaminase

CDA / Cytidine Deaminase is an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.

Gene Name: cytidine deaminase
Synonyms: CDA, Cytidine aminohydrolase, Cytidine deaminase, Small cytidine deaminase, CDD, Cytosine nucleoside deaminase
Target Sequences: NM_001785 NP_001776.1

Publications (1)

1
The Impact of dUTPase on Ribonucleotide Reductase-Induced Genome Instability in Cancer Cells. Chen CW, Tsao N, Huang LY, Yen Y, Liu X, Lehman C, Wang YH, Tseng MC, Chen YJ, Ho YC, Chen CF, Chang ZF. Cell reports. 2016 August;16:1287-1299. (Human) [Full Text Article] [PubMed:27452458] Related Antibodies: LS-B1823.

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Antibodies (37)
Primary (37)
CDA / Cytidine Deaminase (37)
Human (37)
Mouse (11)
Rat (4)
Bovine (3)
Chimpanzee (3)
Gibbon (3)
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IHC (8)
IHC-P (4)
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ELISA (9)
ICC (1)
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IP (1)
Peptide-ELISA (1)
rabbit (36)
mouse (1)
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IgG (19)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (36)
921CT14.2.1 (1)
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APC Conjugated (2)
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Cy3 Conjugated (1)
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aa2-146 (8)
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N-Terminus (1)
aa118-146 (1)
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CDA / Cytidine Deaminase Antibody - Anti-Cytidine Deaminase antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CDA / Cytidine Deaminase Antibody - Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC-P, WB
Unconjugated
50 µl/$460
CDA / Cytidine Deaminase Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
CDA / Cytidine Deaminase Antibody - CDA Antibody western blot of HeLa cell line lysates (35 ug/lane). The CDA antibody detected the CDA protein (arrow).
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CDA / Cytidine Deaminase Mouse anti-Human Monoclonal (921CT14.2.1) Antibody
Human
WB
Unconjugated
400 µl/$393
CDA / Cytidine Deaminase Antibody - Western blot of lysates from HeLa cell line, human liver and mouse kidney tissue lysate(from left to right), using CDA Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal (aa51-83) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
CDA / Cytidine Deaminase Antibody - Immunohistochemistry of paraffin-embedded human liver cancer using CDA Antibody at dilution of 1:100 (40x lens).
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CDA / Cytidine Deaminase Antibody - 1:100 staining human lymph node tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CDA / Cytidine Deaminase Antibody - Immunohistochemistry of paraffin-embedded human spleen tissue using CDA Antibody at dilution of 1:50
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
CDA / Cytidine Deaminase Antibody - Western blot of Cytidine deaminase antibody at 2 ug/ml + 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 16.5 kDa. Observed band size: 20 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
CDA / Cytidine Deaminase Antibody - Western blot of Cytidine deaminase antibody at 2 ug/ml + 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 16.5 kDa. Observed band size: 20 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
CDA / Cytidine Deaminase Antibody - Western blot of Cytidine deaminase antibody at 2 ug/ml + 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 16.5 kDa. Observed band size: 20 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
CDA / Cytidine Deaminase Antibody - IHC staining of FFPE human breast cancer with CDA antibody at 1ug/ml. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
100 µg/$575
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$356; 100 µl/$461
Select
CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$582
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µg/$582
Select
CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µg/$582
Select
CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µg/$582
Select
CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
CDA / Cytidine Deaminase Antibody - CDA / Cytidine Deaminase antibody Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
CDA / Cytidine Deaminase Antibody - Western blot of anti-CDA Antibody in mouse kidney tissue lysates (35 ug/lane). CDA (arrow) was detected using the purified antibody.
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal (aa118-146) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
CDA / Cytidine Deaminase Antibody - Western blot of CDA / Cytidine Deaminase antibody.
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CDA / Cytidine Deaminase Rabbit anti-Human Polyclonal (aa2-146) Antibody
Pig, Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).