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CD9

CD9 molecule

CD9 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis.

Gene Name: CD9 molecule
Family/Subfamily: Tetraspan , not assigned-Tetraspan
Synonyms: CD9, 5H9 antigen, BA2, BA-2/p24 antigen, CD9 antigen, CD9 antigen (p24), DRAP-27, MIC3, MRP-1, Leukocyte antigen MIC3, Tetraspanin-29, TSPAN29, BTCC-1, CD9 molecule, Motility related protein-1, Motility-related protein, TSPAN-29
Target Sequences: NM_001769 NP_001760.1 P21926

Publications (8)

1
Potentials and capabilities of the Extracellular Vesicle (EV) Array. Jørgensen MM, Bæk R, Varming K. Journal of Extracellular Vesicles. 2015 4:26048. (IHC; Human) [PubMed:25862471] [PMC:PMC4393420]
2
Characterization of a Cell-Culturing System for the Study of Contact-Independent Extracellular Vesicle Communication. Revenfeld ALS, Søndergaard EKL, Stensballe A, Bæk R, Jørgensen MM, Varming K. Journal of circulating biomarkers. 2016 February;5:3. (Human) [Full Text Article] [PubMed:28936251] [PMC:PMC5548315]
3
Induction of a Regulatory Phenotype in CD3+ CD4+ HLA-DR+ T Cells after Allogeneic Mixed Lymphocyte Culture; Indications of Both Contact-Dependent and -Independent Activation. Revenfeld ALS, Bæk R, Jørgensen MM, Varming K, Stensballe A. International journal of molecular sciences. 2017 July;18:pii: E1603. (Human) [Full Text Article] [PubMed:28737722] [PMC:PMC5536089]
4
Melanoma-Derived Exosomes Induce PD-1 Overexpression and Tumor Progression via Mesenchymal Stem Cell Oncogenic Reprogramming. Edina Gyukity-Sebestyén, Mária Harmati, Gabriella Dobra, István B Németh, Johanna Mihály, Ágnes Zvara, Éva Hunyadi-Gulyás, Róbert Katona, István Nagy, Péter Horváth, Árpád Bálind, Ábel Szkalisity, Mária Kovács, Tibor Pankotai, Barbara Borsos, Miklós Erdélyi, Zsolt Szegletes, Zoltán J Veréb, Edit I Buzás, Lajos Kemény, Tamás Bíró, Krisztina Buzás. Frontiers in immunology. 2019 November;10:2459. [Full Text Article] [PubMed:31681332] [PMC:PMC6813737]
5
Proteomic Analysis of Plasma Membrane Proteins of Antler Stem Cells Using Label-Free LC?MS/MS. Datao Wang, Hengxing Ba, Chenguang Li, Quanmin Zhao, Chunyi Li. International journal of molecular sciences. 2018 Nov;19:3477. [Full Text Article] [PubMed:30400663] [PMC:PMC6275008] Related Antibodies: LS-C46004.
6
CD9-positive microvesicles mediate the transfer of molecules to Bovine Spermatozoa during epididymal maturation. Caballero JN, Frenette G, Belleann[Character e9]e C, Sullivan R. PloS one. 2013 8:e65364. [Full Text Article] [PubMed:23785420] [PMC:PMC3681974] Related Antibodies: LS-B5962.
7
Effects of pramipexole treatment on the α-synuclein content in serum exosomes of Parkinson's disease patients. Luo HT, Zhang JP, Miao F. Experimental and therapeutic medicine. 2016 12:1373-1376. (IHC, WB; Human) [Full Text Article] [PubMed:27588058] [PMC:PMC4998109] Related Antibodies: LS-C382578.
8
Extracellular Vesicle (EV) Array: microarray capturing of exosomes and other extracellular vesicles for multiplexed phenotyping. Jorgensen M1, Baek R, Pedersen S, Sondergaard EK, Kristensen SR, Varming K. Journal of Extracellular Vesicles. 2013 Jun 18;2: [Full Text Article] [PubMed:24009888] [PMC:PMC3760630] Related Antibodies: LS-C35419.
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Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
CD9 (7)
No (7)
GST (1)
GST, N-terminus (1)
His (1)
His-GST (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Human Cells (1)
Wheat Germ Extract (2)
Purified (1)
Low endotoxin level (1)
CD9 Protein - Purified recombinant protein CD9 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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Human CD9 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65214
HEK 293 Cells
Myc-DDK (Flag)
25.2 kDa
20 µg/$1,107
CD9 Protein - Recombinant Macrophage Inflammatory Protein Related Protein 1 By SDS-PAGE
Select
Human CD9 Protein (Recombinant His-GST) (aa112-195) - LS-G24209
E. coli
His-GST
39.7 kDa
10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198
Select
Human CD9 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75103
293T Cells
Myc-DDK (Flag)
25.2 kDa
20 µg/$150
CD9 Protein - 12.5% SDS-PAGE of human CD9 stained with Coomassie Blue
Select
Human CD9 Protein (Recombinant GST) (Full Length) - LS-G27796
Wheat Germ Extract
GST
51.8 kDa
10 µg/$479; 25 µg/$670
CD9 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Human CD9 Protein (Recombinant GST, N-terminus) (aa112-195) - LS-G58034
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CD9 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
CD9 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99563
HEK 293 Cells
Myc-DDK (Flag)
25.2 kDa
100 µg/$494
Select
Human CD9 Protein (Recombinant His) (Ser112-Ile195) - LS-G97286
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
11 kDa
50 µg/$710; 500 µg/$3,767
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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