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CD86

CD86 molecule

CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. It is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.

Gene Name: CD86 molecule
Synonyms: CD86, Activation B7-2 antigen, B7-2, B7.2, B70, CD86 molecule, CTLA-4 counter-receptor B7.2, CD86 antigen, FUN-1, LAB72, BU63, CD28LG2, Ctla-4 counter-receptors b7.2
Target Sequences: NM_006889 NP_008820.3 P42081

Publications (1)

1
N-docosahexaenoylethanolamine reduces neuroinflammation and cognitive impairment after mild traumatic brain injury in rats. Arina I Ponomarenko, Anna A Tyrtyshnaia, Evgeny A Pislyagin, Inessa V Dyuizen, Ruslan M Sultanov, Igor V Manzhulo. Scientific reports. 2021 January;11:756. [Full Text Article] [PubMed:33436960] [PMC:PMC7804312]

☰ Filters
Products
Proteins (33)
Recombinant (33)
CD86 (33)
Preservative Free (2)
No (33)
6His, C-terminus (7)
6His, N-terminus (1)
AVI-6His, C-terminus (1)
Fc, C-terminus (3)
GST (1)
GST, N-terminus (1)
His (2)
His,C-terminus (5)
His-T7 (2)
Human IgG1 Fc (1)
Mouse IgG2 Fc (1)
Mouse IgG2a Fc, N-terminus (1)
Crab-eating macaque (1)
Human (19)
Monkey-Rhesus (1)
Mouse (7)
Rabbit (2)
Rat (3)
CHO Cells (8)
E. coli (3)
HEK 293 Cells (3)
Human (1)
Human Cells (8)
Mammalian Cells (8)
Wheat Germ Extract (2)
Purified (7)
Low endotoxin level (22)
Biologically active (2)
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.9kD
10 µg/$266; 50 µg/$321; 500 µg/$905; 1 mg/$1,203
Select
CHO Cells
None
52.5 kDa
25 µg/$575
Select
CHO Cells
None
25 µg/$575
Select
CHO Cells
None
52.5 kDa
25 µg/$698
CD86 Protein
Select
CHO Cells
None
52.2 kDa
25 µg/$575
CD86 Protein
Select
CHO Cells
None
52.2 kDa
25 µg/$575
Select
CHO Cells
None
Biologically active
50.0 kDa
100 µg/$349; 20 µg/$268
Select
HEK 293 Cells
Mouse IgG2a Fc, N-terminus
Less than 5.0 EU/mg protein (determined by LAL method).
~65 kDa (SDS-PAGE)
100 µg/$463
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
26.2 kDa
100 µg/$502
CD86 Protein - Recombinant Human B7-2/CD86 (C-Avi-6His) Biotinylated
Select
Human
AVI-6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
28.4 kDa
20 µg/$416; 100 µg/$910
CD86 Protein - 12.5% SDS-PAGE of human CD86 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
64.1 kDa
10 µg/$479; 25 µg/$670
CD86 Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
Select
E. coli
6His, N-terminus
27.9 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
CD86 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
26.8 kDa
100 µg/$483
Select
CHO Cells
Human IgG1 Fc
Less than 0.06 EU/µg protein (determined by LAL method).
100 µg/$463
Select
CHO Cells
Mouse IgG2 Fc
Less than 0.06 EU/µg protein (determined by LAL method).
100 µg/$463
Select
HEK 293 Cells
None
Less than 0.2 EU/µg protein (determined by LAL method).
65-80 kDa
100 µg/$423; 1 mg/$1,475
CD86 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Mammalian Cells
6His, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
26.69 kDa
50 µg/$356; 10 µg/$259; 1 mg/$2,064; 500 µg/$1,538
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
26.69 kDa
10 µg/$248; 50 µg/$317
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.9 kDa
10 µg/$248; 50 µg/$317
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
26.3 kDa
10 µg/$266; 50 µg/$317
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.9 kDa
10 µg/$266; 50 µg/$317
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
52.5 kDa
10 µg/$253; 50 µg/$332
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
52.2 kDa
10 µg/$233; 50 µg/$277
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.7 kDa
10 µg/$248; 50 µg/$296
Viewing 1-25 of 33 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).