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CD84 / SLAMF5

CD84 molecule

Plays a role as adhesion receptor functioning by homophilic interactions and by clustering. Recruits SH2 domain-containing proteins SH2D1A/SAP. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway. May serve as a marker for hematopoietic progenitor cells.

Gene Name:	CD84 molecule
Family/Subfamily:	Immunoglobulin , not assigned-Immunoglobulin
Synonyms:	CD84, CD84 antigen, Cell surface antigen MAX.3, CD84 molecule, HCD84, Hly9-beta, LY9B, Leukocyte antigen CD84, SLAMF5, MCD84, SLAM family member 5
Target Sequences:	NM_003874 NP_003865.1 Q9UIB8

Publications (1)

Signaling Lymphocyte Activation Molecule Family 5 Enhances Autophagy and Fine-Tunes Cytokine Response in Monocyte-Derived Dendritic CellsviaStabilization of Interferon Regulatory Factor 8. Agod Z, Pazmandi K, Bencze D, Vereb G, Biro T, Szabo A, Rajnavolgyi E, Bacsi A, Engel P, Lanyi A. Frontiers in immunology. 2018 January;9:62. (Human) [Full Text Article] [PubMed:29434592] [PMC:PMC5790988] Related Antibodies: LS-C134663.

Human CD84 / SLAMF5 (Custom) ELISA Kit - LS-F65993

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Price:

1 Plate/$783

Mouse CD84 / SLAMF5 (Custom) ELISA Kit - LS-F65859

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Price:

1 Plate/$783

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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