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CD82

CD82 molecule

This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Name: CD82 molecule
Family/Subfamily: Tetraspan , not assigned-Tetraspan
Synonyms: CD82, 4F9, C33, C33 antigen, CD82 molecule, GR15, IA4, Inducible membrane protein R2, KAI1, Kangai 1, R2, R2 leukocyte antigen, SAR2, ST6, Tetraspanin-27, Tspan-27, TSPAN27, CD82 antigen, Leukocyte surface antigen r2, Metastasis suppressor Kangai-1
Target Sequences: NM_002231 NP_002222.1 P27701

Publications (1)

1
CD82 is a marker to isolate ß cell precursors from human iPS cells and plays a role for the maturation of ß cells. Ami Watanabe, Anna Tanaka, Chizuko Koga, Masahito Matsumoto, Yasushi Okazaki, Tatsuya Kin, Atsushi Miyajima. Scientific reports. 2021 May;11:9530. [Full Text Article] [PubMed:33953224] [PMC:PMC8100138] Related Antibodies: LS-B15130, LS-C742189.

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
CD82 (6)
No (6)
Fc, N-terminus (1)
GST (1)
His,C-terminus (1)
His-SUMO (1)
Myc-DDK (Flag) (2)
Human (4)
Mouse (1)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Human (1)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (2)
CD82 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
29.4 kDa
20 µg/$150
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HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
15 kDa
50 µg/$843
CD82 Protein - Recombinant Human CD82 (N-Fc)
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Human
Fc, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
40.3 kDa
10 µg/$353; 50 µg/$703
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E. coli
His-SUMO
29.5 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
CD82 Protein - 12.5% SDS-PAGE of human CD82 stained with Coomassie Blue
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Wheat Germ Extract
GST
55.11 kDa
10 µg/$479; 25 µg/$670
CD82 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
29.4 kDa
100 µg/$494
Viewing 1-6 of 6 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).