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CD80
CD80 molecule
Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.
| Gene Name: | CD80 molecule |
| Synonyms: | CD80, Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CD80 antigen, LAB7, CD80 molecule, CTLA-4 counter-receptor B7.1 |
| Target Sequences: | NM_005191 NP_005182.1 P33681 |
Publications (3)
1
Self-reactive human CD4 T cell clones form unusual immunological synapses. Schubert DA, Gordo S, Sabatino JJ, Vardhana S, Gagnon E, Sethi DK, Seth NP, Choudhuri K, Reijonen H, Nepom GT, Evavold BD, Dustin ML, Wucherpfennig KW. The Journal of experimental medicine. 2012 209:335-52.
[PubMed:22312112]
[PMC:PMC3280872]
Related Antibodies: LS-C40976.
2
Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa. Mrinal K Sarkar, Grace A Hile, Lam C Tsoi, Xianying Xing, Jianhua Liu, Yun Liang, Celine C Berthier, William R Swindell, Matthew T Patrick, Shuai Shao, Pei-Suen Tsou, Ranjitha Uppala, Maria A Beamer, Anshika Srivastava, Stephanie L Bielas, Paul W Harms, Spiro Getsios, James T Elder, John J Voorhees, Johann E Gudjonsson , J Michelle Kahlenberg. Annals of the rheumatic diseases. 2018 Nov;77:1653-1664. [Full Text Article]
[PubMed:30021804]
[PMC:PMC6185784]
Related Antibodies: LS-C115529.
3
Leishmania major infection activates NF-kappaB and interferon regulatory factors 1 and 8 in human dendritic cells. Jayakumar A, Donovan MJ, Tripathi V, Ramalho-Ortigao M, McDowell MA. Infection and immunity. 2008 76:2138-48.
[PubMed:18316378]
[PMC:PMC2346706]
Related Antibodies: LS-C40976.
☰ Filters
Products
Proteins
(33)
Type
Recombinant
(33)
Target
CD80
(33)
Format
Preservative Free
(1)
Publications
No
(33)
Tag
10His, N-terminus
(1)
6His, C-terminus
(8)
DDK (Flag)-His, C-terminus
(1)
Fc, C-terminus
(4)
Fc-His, C-terminus
(1)
GST
(2)
His,C-terminus
(3)
His-GST
(1)
Human IgG1 Fc
(1)
mFc, C-terminus
(1)
Mouse IgG2 Fc
(2)
Myc-DDK (Flag)
(1)
Species
Crab-eating macaque
(2)
Human
(18)
Mouse
(9)
Rabbit
(2)
Rat
(2)
Source
CHO Cells
(8)
E. coli
(2)
HEK 293 Cells
(6)
Human Cells
(7)
Mammalian Cells
(8)
Wheat Germ Extract
(2)
Purification
Purified
(9)
Low Endotoxin Level
Low endotoxin level
(22)
Biologically Active
Biologically active
(3)
CHO Cells
Mouse IgG2 Fc
Biologically active
Less than 0.06 EU/µg protein (determined by LAL method).
100 µg/$463
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.7kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
E. coli
10His, N-terminus
32.8 kDa
100 µg/$1,801; 20 µg/$1,247
CHO Cells
None
Biologically active
51.2 kDa
100 µg/$349; 20 µg/$268
HEK 293 Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
50.7 kDa
100 µg/$502
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.1 kDa
100 µg/$502
HEK 293 Cells
Fc-His, C-terminus
51 kDa
20 µg/$1,107
HEK 293 Cells
DDK (Flag)-His, C-terminus
27 kDa
20 µg/$1,107
E. coli
His-GST
53.7 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
Wheat Germ Extract
GST
53.68 kDa
10 µg/$479; 25 µg/$670
Wheat Germ Extract
GST
54.34 kDa
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
29.3 kDa
20 µg/$1,107
Human Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
25.5 kDa
100 µg/$926
CHO Cells
Human IgG1 Fc
Less than 0.06 EU/µg protein (determined by LAL method).
100 µg/$463
CHO Cells
Mouse IgG2 Fc
Less than 0.06 EU/µg protein (determined by LAL method).
100 µg/$463
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.7kD
10 µg/$248; 50 µg/$328; 500 µg/$1,585; 1 mg/$2,157
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
50.8kD
10 µg/$233; 50 µg/$277; 500 µg/$725; 1 mg/$1,113
HEK 293 Cells
None
Less than 0.2 EU/µg protein (determined by LAL method).
75-80 kDa
1 mg/$1,475; 100 µg/$444; 50 µg/$346
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.7kD
10 µg/$248; 50 µg/$277; 500 µg/$725; 1 mg/$1,113
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.6kD
10 µg/$248; 50 µg/$277; 500 µg/$725; 1 mg/$1,113
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.5kD
10 µg/$248; 50 µg/$277; 500 µg/$785; 1 mg/$1,067
CHO Cells
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
The 449 amino acid recombinant protein has a predicted molecular mass of approximately 51 kD. The protein migrates at approximately 72 kD in DTT-reducing conditions and at approximately 150 kD in non-reducing conditions by SDS-PAGE. The predicted N-termin
25 µg/$306; 100 µg/$436
Viewing 1-25
of 33
product results
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