Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

CD68

CD68 molecule

CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

Gene Name: CD68 molecule
Synonyms: CD68, CD68 antigen, gp110, SCARD1, CD68 molecule, LAMP4, Macrophage antigen CD68, Macrosialin
Target Sequences: NM_001251 NP_001242.2 P34810

Publications (5)

1
Aneurysm Severity is Increased by Combined Mmp-7 Deletion and N-cadherin Mimetic (EC4-Fc) Over-Expression. Lyon CA, Williams H, Bianco R, Simmonds SJ, Brown BA, Wadey KS, Smith FCT, Johnson JL, George SJ. Scientific reports. 2017 December;7:17342. (Mouse) [Full Text Article] [PubMed:29229950] [PMC:PMC5725451]
2
CD1b-restricted GEM T cell responses are modulated by Mycobacterium tuberculosis mycolic acid meromycolate chains. Chancellor A, Tocheva AS, Cave-Ayland C, Tezera L, White A, Al Dulayymi JR, Bridgeman JS, Tews I, Wilson S, Lissin NM, Tebruegge M,, Marshall B,, Sharpe S, Elliott T, Skylaris CK, Essex JW, Baird MS, Gadola S, Elkington P,, Mansour S. Proceedings of the National Academy of Sciences of the United States of America. 2017 December;114:E10956-E10964. [Full Text Article] [PubMed:29158404] [PMC:PMC5754766] Related Antibodies: LS-C188452.
3
Reduced patency in left-sided arteriovenous grafts in a porcine model. Shirley Liu, Tun Wang, Juan Wang, Toshihiko Isaji, Shun Ono, Arash Fereydooni, Ryosuke Taniguchi, Yutaka Matsubara, Laura E Niklason, Alan Dardik. Journal of vascular surgery. 2020 July;72:305-317.e6. [Full Text Article] [PubMed:31699515] [PMC:PMC7196525] Related Antibodies: LS-C187543.
4
Adenovirus 14p1 Immunopathogenesis during Lung Infection in the Syrian Hamster. Jay R Radke, Hunter J Covert, Fredrick Bauer, Vijayalakshmi Ananthanarayanan, James L Cook. Viruses. 2020 May;12: [Full Text Article] [PubMed:32486177] [PMC:PMC7354616]
5
An ex vivo physiologic and hyperplastic vessel culture model to study intra-arterial stent therapies. Juan Wang, Mehmet H Kural, Jonathan Wu, Katherine L Leiby, Vinayak Mishra, Taras Lysyy, Guangxin Li, Jiesi Luo, Allison Greaney, George Tellides, Yibing Qyang, Nan Huang, Laura E Niklason. Biomaterials. 2021 August;275:120911. [Full Text Article] [PubMed:34087584] [PMC:PMC9195126] Related Antibodies: LS-C187543.
more

☰ Filters
Products
Proteins (16)
Over-Expression Lysate (4)
Recombinant (12)
CD68 (16)
No (16)
6His, N-terminus (1)
Fc (1)
Fc, C-terminus (1)
GST, N-terminus (1)
His (4)
His,C-terminus (1)
His-GST (1)
His-SUMO (1)
Human IgG1 Fc (1)
Myc-DDK (Flag) (4)
Human (9)
Mouse (3)
Rat (2)
293T Cells (2)
Baculovirus (1)
CHO Cells (1)
E. coli (5)
HEK 293 Cells (3)
Human (1)
Human Cells (1)
Wheat Germ Extract (1)
Yeast (1)
Purified (4)
Low endotoxin level (6)
Biologically active (1)
CD68 Protein - Recombinant Scavenger Receptor Class D Member 1 By SDS-PAGE
Select
E. coli
His-GST
61.4 kDa
50 µg/$502; 10 µg/$291; 200 µg/$1,002; 100 µg/$802; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
CD68 Protein - Recombinant Human CD68/SR-D1 (C-Fc)
Select
Human
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
58.5 kDa
10 µg/$308; 50 µg/$502
CD68 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
37.2 kDa
100 µg/$494
CD68 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
34.5 kDa
100 µg/$494
Select
E. coli
His-SUMO
44.7 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
Select
Yeast
His
30.7 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
CD68 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CD68 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
34.5 kDa
20 µg/$150
CD68 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
37.2 kDa
20 µg/$150
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
56.5 kDa
100 µg/$843
Select
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
32.9 kDa
100 µg/$721
Select
CHO Cells
Human IgG1 Fc
Biologically active
Less than 0.06 EU/µg protein (determined by LAL method).
100 µg/$587
CD68 Protein
Select
E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
Select
E. coli
116 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
12.87 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
30.9 kDa
100 µg/$721
Select
E. coli
6His, N-terminus
28.5 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
Viewing 1-16 of 16 product results


Filtered By:
Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).