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CD66c / CEACAM6

carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)

CD66c / CEACAM6 encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19.

Gene Name: carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
Family/Subfamily: CEA , not assigned-CEA
Synonyms: CEACAM6, CD66c, CD66c antigen, CEAL, NCA, Normal cross-reacting antigen
Target Sequences: NM_002483 NP_002474.4 P40199

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).