CD59

CD59 molecule, complement regulatory protein

CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

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Products

ELISA Kits (17)

Type

Custom (1)

Sandwich (15)

Sandwich CLIA (1)

Target

CD59 (17)

Reactivity

Human (7)

Mouse (1)

Rat (2)

Chicken (1)

Guinea pig (1)

Monkey (1)

Pig (1)

Porcine (1)

Rabbit (1)

Sheep (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (2)

96-Well Strip Plate (14)

Publications

No (17)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (10)

Serum (10)

Tissue Homogenates (2)

Urine (1)

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Human CD59 (Sandwich ELISA) ELISA Kit - LS-F6544

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

12.5 - 800 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum

Price:

1 Plate/$798

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Human CD59 (Sandwich ELISA) ELISA Kit - LS-F11090

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human CD59 (Sandwich ELISA) ELISA Kit - LS-F3563

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

40.96 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$700

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Rat CD59 (Sandwich ELISA) ELISA Kit - LS-F11089

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Chicken CD59 (Sandwich ELISA) ELISA Kit - LS-F47288

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

1.563 - 100 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Guinea pig CD59 (Sandwich ELISA) ELISA Kit - LS-F47289

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

1.563 - 100 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Porcine CD59 (Sandwich ELISA) ELISA Kit - LS-F47291

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Monkey CD59 (Sandwich ELISA) ELISA Kit - LS-F47290

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Rabbit CD59 (Sandwich ELISA) ELISA Kit - LS-F47292

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

1.25 - 80 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Sheep CD59 (Sandwich ELISA) ELISA Kit - LS-F47293

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$760

Select

Pig CD59 (Custom ELISA) ELISA Kit - LS-F19284

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Human CD59 (CLIA) ELISA Kit - LS-F29527

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

15.625 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Human CD59 (Sandwich ELISA) ELISA Kit - LS-F23428

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Human CD59 (Sandwich ELISA) ELISA Kit - LS-F27168

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

100 - 2500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

Select

Rat CD59 (Sandwich ELISA) ELISA Kit - LS-F35459

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human CD59 (Sandwich ELISA) ELISA Kit - LS-F35456

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse CD59 (Sandwich ELISA) ELISA Kit - LS-F9560

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Urine

Price:

1 Plate/$818

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