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CD55

CD55 molecule, decay accelerating factor for complement (Cromer blood group)

This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.

Gene Name: CD55 molecule, decay accelerating factor for complement (Cromer blood group)
Synonyms: CD55, CD55 antigen, Decay-accelerating factor, TC, CR, CROM, DAF
Target Sequences: NM_000574 NP_000565.1 P08174

Publications (2)

1
Longitudinally extensive NMO spinal cord pathology produced by passive transfer of NMO-IgG in mice lacking complement inhibitor CD59. Zhang H, Verkman AS. Journal of autoimmunity. 2014 53:67-77. (WB; Mouse) [Full Text Article] [PubMed:24698947] [PMC:PMC4162764] Related Antibodies: LS-C34553.
2
Distinct immunocyte-promoting and adipocyte-generating stromal components coordinate adipose tissue immune and metabolic tenors. Raul German Spallanzani, David Zemmour, Tianli Xiao, Teshika Jayewickreme, Chaoran Li, Paul J Bryce, Christophe Benoist, Diane Mathis. Science immunology. 2019 May;4: [Full Text Article] [PubMed:31053654] [PMC:PMC6648660] Related Antibodies: LS-C62832.

☰ Filters
Products
Proteins (15)
Over-Expression Lysate (4)
Recombinant (11)
CD55 (15)
No (15)
6His, C-terminus (2)
Fc (2)
GST (1)
GST, N-terminus (1)
His (4)
His-T7 (1)
Myc-DDK (Flag) (4)
Human (9)
Mouse (2)
Rat (2)
293T Cells (2)
E. coli (3)
HEK 293 Cells (2)
Human Cells (5)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (4)
Low endotoxin level (6)
CD55 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
41.2 kDa
100 µg/$494
CD55 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
48.72 kDa
100 µg/$494
CD55 Protein - Recombinant  Decay Accelerating Factor By SDS-PAGE
Select
E. coli
His-T7
31.6 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
CD55 Protein - 12.5% SDS-PAGE of human DAF stained with Coomassie Blue
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Wheat Germ Extract
GST
67.8 kDa
10 µg/$479; 25 µg/$670
CD55 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
41.2 kDa
20 µg/$150
CD55 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
48.72 kDa
20 µg/$150
CD55 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
61.7 kDa
100 µg/$721
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
64.5 kDa
100 µg/$721
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
37.2 kDa
100 µg/$721
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
36.5 kDa
100 µg/$721
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
36kD
10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
36.0 kDa
10 µg/$269; 50 µg/$368
CD55 Protein - Recombinant Decay Accelerating Factor By SDS-PAGE
Select
E. coli
His
14.7 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
CD55 Protein - Recombinant Decay Accelerating Factor By SDS-PAGE
Select
E. coli
His
28.1 kDa
10 µg/$273; 50 µg/$392; 100 µg/$625; 200 µg/$782; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).